Stanbery AG, Newman ZR, Barton GM. Dysregulation of TLR9 in neonates leads to fatal inflammatory disease driven by IFN-γ. Proc Natl Acad Sci USA. (2020) 117:3074-3082

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Majer O*, Liu B*, Kreuk LSM, Krogan N, Barton GM. Unc93b1 recruits Syntenin-1 to dampen TLR7 signaling and prevent autoimmunity. Nature (2019) 575:366-370. *equal contribution

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Majer O, Liu B, Woo BJ, Kreuk LSM, Van Dis E, Barton GM. Release from Unc93b1 reinforces compartmentalized activation of select Toll-like receptors. Nature (2019) 575:371-374.

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Walsh CM, Hill RZ, Schwendinger-Schreck J, Deguine J, Brock EC, Kucirek N, Rifi Z, Wei J, Gronert K, Brem RB, Barton GM, Bautista DM. Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis. eLIFE (2019) 8:e48448.

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Kreuk LS, Koch MA, Slayden LC, Lind NA, Chu S, Savage HP, Kantor AB, Baumgarth N, Barton GM. B cell receptor and Toll-like receptor signaling coordinate to control distinct B-1 responses to both self and microbiota. eLife (2019) 8:e47015

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Ansaldo E, Slayden LC, Ching KL, Koch MA, Wolf NK, Plichta DR, Brown EM, Graham DB, Xavier RJ, Moon JJ, Barton GM. Akkermansia muciniphila induces intestinal adaptive immune responses during homeostasis. Science (2019) 364:1179-1184.

 

Roberts AW, Popov LM, Mitchell G, Ching KL, Licht DJ, Golovkine G, Barton GM, Cox JS. Cas9+ conditionally immortalized macrophages as a tool for bacterial pathogenesis and beyond. eLife (2019) 8:e45957.

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Price AE, Shamardani K, Lugo KA, Deguine J, Roberts AW, Lee BL, Barton GM. A Map of Toll-like Receptor Expression in the Intestinal Epithelium Reveals Distinct Spatial, Cell Type-Specific and Temporal Patterns. Immunity (2018) 49:560-575.e6 .

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Roberts AW, Lee BL, Deguine J, John S, Schlomchik MJ, Barton GM. Tissue-Resident Macrophages Are Localy Programmed for Silent Clearance of Apoptotic Cells. Immunity (2017) 47:913-927.

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Deguine J, Wei J, Barbalat R, Gronert K, Barton GM. Local TNFR1 Signaling Licenses Murine Neutrophils for Increased TLR-Dependent Cytokine and Eicosanoid Production. J Immunol (2017) 198:2865-2875.

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Koch MA, Reiner GL, Lugo KA, Kreuk LS, Stanbery AG, Ansaldo E, Seher TD, Ludington WB, Barton GM. Maternal IgG and IgA Antibodies Dampen Mucosal T Helper Cell Responses in Early Life. Cell (2016) 165:827-841.

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Newman ZR, Young JM, Ingolia NT, Barton GM. Differences in codon bias and GC content contribute to the balanced expression of TLR7 and TLR9. Proc Natl Acad Sci U S A. (2016) 113:E1362-1371.

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Sivick KE, Arpaia N, Reiner GL, Lee BL, Russell BR, Barton GM. Toll-like receptor-deficient mice reveal how innate immune signaling influences salmonella virulence strategies. Cell Host Microbe (2014) 15:203-213.

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Deguine J, Lee BL, Newman ZR, Barton GM. No antigen-presentation defect in Unc93b1(3d/3d) 3d mice. Nature Immunology (2013) 14: 1101-1102.

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Lee BL, Moon JE, Shu JH, Yuan L, Newman ZR, Schekman R, Barton GM. UNC93B1 mediates differential trafficking of endosomal TLRs, eLife (2013) 2:e00291.

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Chiang C, Engel A, Opaluch AM, Ramos I, Maestre AM, Secundino I, De Jesus P, Nguyen QT, Welch B, Bonamy GM, Miraglia LJ, Orth AP, Nizet V, Fernandez-Sesma A, Zhou Y, Barton GM, Chanda SK. Cofactors Required for TLR7- and TLR9- Dependent innate Immune Responses, Cell Host and Microbe (2012) 35:306-318.

 

Mouchess ML, Arpaia N, Souza G, Barbalat R, Ewald SE, Lau L, Barton GM. Transmembrane Mutations in Toll-like Receptor 9 Bypass the Requirement for Ectodomain Proteolysis and Induce Fatal Inflammation, Immunity (2011) 35:721-732.

 

Zanoni I, Ostuni R, Marek LR, Barresi S, Barbalat R, Barton GM, Granucci F, Kagan JC. CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4, Cell (2011) 147:868-880.

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Ewald SE, Engel A, Lee J, Wang M, Bogyo M, Barton GM. Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase, Journal of Experimental Medicine (2011) 208: 643-651.

 

Arpaia N, Godec J, Lau L, Sivick KE, McLaughlin LM, Jones MB, Dracheva T, Peterson SN, Monack DM, Barton GM. TLR signaling is required for Salmonella typimurium virulence, Cell (2011) 144:675-688. Video abstract can be found here.

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Barbalat R, Lau L, Locksley RM, Barton GM. Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands, Nature Immunology (2009) 10:1200-1207.

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Ewald SE, Lee BL, Lau L, Wickliffe KE, Shi GP, Chapman HA, Barton GM. The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor, Nature (2008) 456:658-662.

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